Neutrophil percentage optimal range and reference range

Compiled by Alina Radu, founder of Sera, from the published sources below · Last reviewed November 9, 2026

Sera's bands for Neutrophil percentage:

  • Optimal 45 – 65 %; sufficient 40 – 70 %; out of range below 40 or above 70 %.

Evidence grade: Published reference interval. A band that primarily reflects a published adult laboratory or population reference interval. It is not necessarily applicable to every assay or laboratory.

All units

UnitOptimalSufficientOut of range
%45 – 6540 – 70below 40 or above 70

What the evidence says

The acceptable band starts at 40%, the lower reference limit MedlinePlus gives. Its upper edge of 70% is not a published limit: MedlinePlus ends at 60% and a US laboratory catalogue at 80%. The optimal band of 45% to 65% has no published source. A percentage shifts whenever another cell type changes, so the absolute neutrophil count is the more meaningful figure and the two are read together with the total white cell count.

Sources

  • Blood differential test — MedlinePlus Medical Encyclopedia, US National Library of Medicine, 2025 · Government / public-health guidanceNormal neutrophils are 40% to 60% of white cells. Matches Sera's sufficient lower edge of 40; its upper limit of 60 is below Sera's 70.
  • AUTO DIFF (test catalog entry) — MHCC Laboratory, test catalog powered by Mayo Clinic Laboratories, 2026 · Laboratory / reference-interval sourceAdult neutrophils 50% to 80%. A wider and higher interval than Sera's: its upper limit of 80 is above Sera's 70 and its lower limit of 50 is above Sera's 40. The page shows no review date; 2026 is the copyright year.

What Neutrophils % measures

The share of your white blood cells that are neutrophils.

A high share can point to a bacterial infection, while a low share can point to a viral one.

Related blood cell health markers

See Neutrophil percentage in the full list of biomarker ranges

About the author

Alina Radu is the founder of Sera and a software engineer. The idea started with her own Hashimoto's tests, scattered across years without the big picture. She is not a clinician: these ranges are compiled from the published sources linked on each page, with every source named. Alina Radu on LinkedIn

This page is a reference for practitioners, not medical advice. Sera's bands are practitioner targets for structured review, not diagnostic thresholds, and Sera does not diagnose or recommend treatment. Read a result alongside the interval printed by the issuing laboratory and the client's history and symptoms. Range set: Sera Production, version 1.0, last reviewed November 9, 2026.